Lipid Nanoparticle CAR Engineering Reveals Synergy Between T Cells and Macrophages Against Leukemia
A new study shows that lipid nanoparticle-delivered CAR mRNA engineers both human T cells and macrophages against CD19-positive leukemia cells, ...
Tag: phagocytosis
Snake Virus Study Reveals Hidden Immune Damage Behind a Deadly Reptile Disease
A comprehensive study of 133 boa constrictors shows that boid inclusion body disease selectively impairs phagocytic immune cells and lowers ...
The Don’t Eat Me Signal: How CD47 Shapes Cell Clearance in Cancer, Heart Disease and the Brain
A new review details how the CD47 don't eat me signal regulates efferocytosis and shapes disease outcomes in cancer, atherosclerosis ...
Sea Cucumber Immune Cells Revealed in Unprecedented Detail by Single-Cell Sequencing
A single-cell RNA sequencing study of the sea cucumber Holothuria forskali has identified ten distinct coelomocyte populations, including a clearly ...
Immune Checkpoint TREM2 Emerges as a Switch to Supercharge CAR Macrophages Against Breast Cancer
New research shows that blocking the TREM2 receptor reprograms HER2-targeted CAR macrophages from suppressive to inflammatory, tumor-engulfing cells in breast ...
Immortalized lung macrophage cell line keeps primary-cell identity, offering new tool for respiratory research
Researchers have created an hTERT-immortalized mouse alveolar macrophage cell line that proliferates indefinitely while retaining the surface markers, gene expression ...
Diesel Soot Paralyzes the Lung’s Resident Scavenger Cells, New Study Finds
New research shows diesel particulate matter disables the lung's resident alveolar macrophages by disrupting actin-driven movement and bacterial engulfment, causing ...
Macrophages move captured proteins onto their own surface during live-cell uptake
New research shows that macrophages can transfer functionally active proteins from engulfed live cells onto their own surface rather than ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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