Bacteriophages could help oncolytic viruses penetrate cold tumors
A 2026 review proposes that bacteriophage-derived delivery, barrier-breaching and immune-stimulation features could help oncolytic viruses penetrate cold tumors and stimulate ...
Tag: phage display
Phage screening identifies candidate tuberculosis peptides for HLA-E
A phage-display and computational screen prioritized 14 Mycobacterium tuberculosis fragments as candidate HLA-E ligands, but experimental validation is still required.
Synthetic Nanobody Library Yields New Resin for Purifying Clotting Factor VII
Researchers built a working immunoaffinity purification resin for recombinant coagulation factor VII using nanobody binders discovered from a fully synthetic ...
Engineered Exosomes Deliver Regenerative Cargo Directly to Neural Stem Cells After Spinal Cord Injury
Researchers have engineered exosomes displaying a phage-display-derived targeting peptide and enriched with Apelin, achieving preferential delivery to endogenous neural stem ...
Protoplast Transfection Unlocks Rapid Engineering of Heat-Loving Phage TP-84
Researchers have developed an optimized protoplast-based system that enables efficient transfection, rebooting, propagation, and DNA isolation of the thermophilic bacteriophage ...
Synthetic antibody fragment lights up human macrophages in PET scans
Researchers have developed the first immunoPET tracer targeting human CD68, a synthetic zirconium-89-labeled antibody fragment that visualized macrophages in mouse ...
New Synthetic Nanobody Library Streamlines Cryo-EM Studies of Small Proteins
Researchers have engineered S1.0, a ribosome-display synthetic nanobody library that yields high-affinity binders compatible with the Legobody cryo-EM toolkit without ...
Tiny red-light switch FenixS–Ash1 delivers ultralow-background optogenetic control
Scientists have engineered FenixS and Ash1, a compact biliverdin-binding protein pair whose binding affinity rises more than 1,200-fold under far-red ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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