New Myosin-Blocking Drug Reopens Blocked Capillaries After Heart Attacks and Kidney Injury
A new study in Nature shows that the experimental compound R(+)2501, a selective inhibitor of smooth muscle myosin, relaxes capillary ...
Tag: pericytes
Pericyte Loss and Inflamed Blood Vessel States Revealed in Brain Small Vessel Disease
A single-vessel analysis of human brain tissue shows that pericyte loss and endothelial activation are partially dissociated processes defining three ...
Bioprinted Blood–Brain–Tumor Barrier Spheroids Put a ROS-Producing Ruthenium Drug to the Test Against Glioblastoma
Researchers built a 3D bioprinted blood–brain–tumor barrier spheroid that self-organizes into barrier and tumor layers and showed that a ROS-producing ...
Hedgehog-Responsive Perivascular Cells Emerge as Master Switches of Blood Vessel Repair and Disease
A new review synthesizes a decade of evidence showing that GLI1-positive perivascular cells act as state-dependent regulators of angiogenesis, capable ...
Aging Hormone Signal Reveals Hidden Trigger of Age-Related Hearing Loss
New research in Aging Cell reveals that age-related decline in IGF-1 disables a mitochondrial protein in cochlear pericytes, triggering TGF-beta/Smad2-driven ...
New Sequencing Methods Capture the Brain’s Hidden Vascular Cells
A newly published Nature Protocols paper details VINE-seq and MultiVINE-seq, streamlined workflows that isolate brain vessels and extract their nuclei ...
Pericyte-like cells may help shape the immune landscape of glioblastoma
New research shows that FAP-positive pericyte-like cells in glioblastoma promote the differentiation of monocytes into immunosuppressive tumor-associated macrophages.
Soluble receptor variants fine-tune placental blood vessel growth, study finds
A new study shows that soluble PDGFRβ isoforms, produced under hypoxic conditions in the developing placenta, act as feedback modulators ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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