Injecting the Immune System: Long-Acting TLR7/8 Agonist Shows Promise Against Oral Cancer
A small German cohort study reports that injecting a slow-release TLR7/8 agonist into oral tumors before surgery, combined with systemic ...
Tag: pembrolizumab
Cancer Drug Triggers Rare Blistering Skin Disease That Masqueraded as Something Else
A new case report describes how the immunotherapy drug pembrolizumab triggered pemphigoid nodularis, a rare blistering skin disease that initially ...
When Cancer Type Stops Mattering: The High-Stakes Bet on Tumour-Agnostic Immunotherapy
A landmark review argues that tumour-agnostic immunotherapy succeeds only when biological rationale, validated biomarkers and health-system infrastructure are aligned, using ...
Immune-Boosted Chemo Cuts Death Risk by a Third in Advanced Esophageal Cancer, Landmark Analysis Finds
A revised meta-analysis of six phase III trials shows first-line PD-1 inhibitor plus chemotherapy reduces the risk of death by ...
Rare POLE P286R-Mutated Lung Cancer Shows Dramatic Response to Immunotherapy
A case report describes the first hepatoid adenocarcinoma of the lung harboring a POLE P286R mutation, which drove hypermutation, mismatch ...
Transparent AI Model Hits 95% Accuracy in Choosing Immunotherapy for Head and Neck Cancer
Researchers in Leipzig corrected a hidden error in a Bayesian network and found the transparent AI model matched real tumor ...
Small Triple-Negative Breast Tumors Blur the Line Between Stage I and Stage II Treatment
A retrospective cohort study of 215 patients finds that small node-negative triple-negative breast cancers show similar biology and outcomes across ...
PD-1 and LAG-3 Double-Positive T Cells Predict Better Gastric Cancer Survival
A multicohort study finds that gastric tumors rich in PD-1 and LAG-3 double-positive CD8 T cells—an activated, pre-exhausted population—are linked ...
Cancer Immunotherapy’s Hidden Heart Risk: Landmark Review Maps Deadly Cardiac Side Effects
A systematic review of 116 case reports reveals that immune checkpoint inhibitors can trigger rare but often fatal heart complications, ...
Antibody-Drug Combination Falls Short in First-Line PD-L1-High Metastatic Lung Cancer Trial
The Phase 3 EVOKE-03/KEYNOTE-D46 trial found that sacituzumab govitecan plus pembrolizumab did not significantly improve progression-free or overall survival compared ...
-
Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
-
University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
-
Bee body mass, pathogens and local climate influence heat tolerance
-
Researchers record first-ever images and data of a shark experiencing a boat strike
-
Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
Embark on a thrilling journey of discovery with Scienmag.com—your ultimate source for cutting-edge breakthroughs. Immerse yourself in a world where curiosity knows no limits and tomorrow’s possibilities become today’s reality!