Two Approved Companion Diagnostics Validate Pembrolizumab Eligibility Across dMMR/MSI-H Tumors
Bridging studies confirm that the Ventana MMR RxDx Panel and FoundationOne CDx reliably identify dMMR/MSI-H tumor patients likely to respond ...
Tag: pembrolizumab
Experimental Drug Tolinapant Boosts Immunotherapy Response in Advanced Solid Tumors
A phase I trial found that the IAP antagonist tolinapant combined with pembrolizumab was well tolerated and produced a 33 ...
Radiotherapy Still Matters in dMMR Endometrial Cancer, Researchers Warn in the Immunotherapy Era
A new Viewpoint in eClinicalMedicine argues that immune checkpoint inhibitors have not yet proven they can replace pelvic radiotherapy in ...
Scientists Uncover Why Esophageal Cancer Shrugs Off PD-1 Blockade
A new study shows that the protein SIRPĪ±, produced by esophageal cancer cells themselves, fuels both tumor growth and T-cell ...
Hidden Fibroblast Subtype Drives Lung Cancer Growth and Weakens Immunotherapy
A multimodal single-cell and spatial study has uncovered a collagen-producing fibroblast subtype enriched in EGFR-mutant non-small cell lung cancer that ...
Real-World Data Confirm Immunotherapy Boost for Aggressive Early Breast Cancer
A real-world study of 95 patients in Tokyo confirms that pembrolizumab combined with chemotherapy before and after surgery delivers event-free ...
Immune Booster Cells Show Promise After Checkpoint Blockers in Liver Cancer
A Taiwanese preliminary study found that following a short course of immune checkpoint inhibitors with infusions of tumor-primed dendritic cells ...
Real-World Data Back Immunotherapy Boost for Early-Stage Triple-Negative Breast Cancer
A new meta-analysis of five observational studies finds that adding pembrolizumab to neoadjuvant chemotherapy in early-stage triple-negative breast cancer appears ...
Injecting the Immune System: Long-Acting TLR7/8 Agonist Shows Promise Against Oral Cancer
A small German cohort study reports that injecting a slow-release TLR7/8 agonist into oral tumors before surgery, combined with systemic ...
Cancer Drug Triggers Rare Blistering Skin Disease That Masqueraded as Something Else
A new case report describes how the immunotherapy drug pembrolizumab triggered pemphigoid nodularis, a rare blistering skin disease that initially ...
-
Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
-
University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
-
Bee body mass, pathogens and local climate influence heat tolerance
-
Researchers record first-ever images and data of a shark experiencing a boat strike
-
Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
Embark on a thrilling journey of discovery with Scienmag.comāyour ultimate source for cutting-edge breakthroughs. Immerse yourself in a world where curiosity knows no limits and tomorrowās possibilities become todayās reality!