Radiation Turns Childhood Brain Tumor Cells Senescent—and Senolytic Drugs Can Kill Them
New research shows that gamma irradiation drives p53 wild-type medulloblastoma cells into a senescent state that senolytic drugs such as ...
Tag: pediatric brain tumor
Childhood Brain Tumor Study Uncovers KDM2B as a Selective Epigenetic Vulnerability
A comprehensive epigenomic map of medulloblastoma reveals that the chromatin regulator KDM2B sustains the highest-risk tumor subgroups by locking neuronal ...
Molecular Fingerprints Reshape the Fight Against Childhood Brain Tumors Above the Tentorium
A comprehensive new review explains how ZFTA and YAP1 gene fusions have redefined the diagnosis and treatment of pediatric supratentorial ...
Massive Single-Cell Map of Childhood Brain Tumor Reveals Immune Signal That Predicts Survival
A single-cell and spatial transcriptomic atlas of medulloblastoma maps developmental hierarchies and identifies the PPIA-BSG tumor-immune signaling axis as an ...
Two Brain Tumors, One Name: Molecular Map Redefines Childhood Posterior Fossa Ependymoma
A comprehensive new review shows that posterior fossa ependymoma comprises two molecularly distinct diseases, PFA and PFB, whose epigenetic differences ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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