Tag: patient-derived organoids

Patient-derived ovarian cancer organoids show that brief chemotherapy exposure reshapes sensitivity to second-line drugs such as cediranib and topotecan without ...

A systematic review of 75 studies maps how organoids, spheroids, tissue slices, and tumor-on-a-chip systems are being used to test ...

A new review maps the laboratory models—from organoids to humanised mice to computational pipelines—that could finally bring personalised treatment to ...

Dutch researchers have shown that combining the bladder chemotherapy drug mitomycin C with ATR kinase inhibitors eradicates patient-derived non-muscle invasive ...

Low-dose inhibition of the motor protein KIF11 rebuilds enhancer–promoter loops at the androgen receptor locus, restoring drug sensitivity in otherwise ...

A new biobank of three-dimensional human tumour models is giving researchers an unprecedented view of the genes that cancers depend ...

Around three million people worldwide live with chronic pancreatitis, a debilitating condition marked by persistent inflammation, scarring, and severe pain. ...

In a groundbreaking study that could reshape the treatment landscape for advanced ovarian cancer, researchers have successfully utilized patient-derived organoids ...

In a groundbreaking study that promises to reshape our understanding of pediatric ulcerative colitis (UC), researchers have leveraged cutting-edge patient-derived ...

In an illuminating advancement that bridges the frontiers of neuroimmunology and regenerative medicine, recent research has unveiled a localized and ...