Tag: patient-derived models

A new review examines how patient-derived tumor organoids retaining immune cells could improve preclinical prediction of immunotherapy response while noting ...

A new review maps how 3D bone marrow models, from spheroids to bioprinted and organ-on-chip systems, are being used to ...

A newly published protocol details a three-component tumor organoid co-culture system with 3D live-cell imaging that quantifies single-cell dynamics of ...

A platinum(IV) prodrug covalently attached to mesoporous silica nanoparticles showed significantly greater cytotoxicity than cisplatin in patient-derived oral squamous cell ...

A five-year National Cancer Institute grant will fund laboratory research into response biomarkers and resistance mechanisms for TROP2-targeted antibody-drug conjugates ...

A 2026 Review argues that osteosarcoma survival and lung spread depend on stage-specific rewiring of extracellular-matrix signaling rather than one ...

Hundreds of patient-derived cancer models expanded dependency mapping and revealed vulnerabilities linked to mutations, cellular states and treatment history, while ...

Researchers engineered fratricide-resistant CD70-targeting natural killer cells that potently killed patient-derived glioblastoma cells in laboratory and animal models.

Researchers have created 3D bioprinted tumor models from the ascites fluid of gastric cancer patients with peritoneal metastasis, preserving tumor ...

A new review argues that conditional reprogramming technology can rapidly expand patient-derived eyelid tumor cells while preserving their cancer-specific features, ...