Tree Bark Polysaccharides Slow Aging in Worms and Flies Through FOXO and Nrf2 Pathways
Polysaccharides from the African tree Pausinystalia macroceras extended lifespan and healthspan in worms and flies by activating the conserved DAF-16/FOXO ...
Tag: Oxidative stress
Spermine Transporter Holds the Key to Gray Mold Fungus Virulence
Scientists have discovered that the transporter BcTpo1 controls how the gray mold fungus Botrytis cinerea manages spermine and oxidative stress, ...
Too Much Cysteine Comes at a Cost: Surplus Amino Acid Triggers Deadly Iron Overload in Cells
A new Nature Metabolism study shows that excess free cysteine disrupts mitochondrial iron homeostasis and triggers a distinct iron-dependent cell ...
Graph Diffusion Extends Metabolomic Signals to Unmeasured Metabolites
Researchers have developed a network propagation method that diffuses statistical signals across a bipartite metabolite–reaction graph, extending metabolomic data exploration ...
A River’s Heavy Metal Burden—and a Fern That Fights Back
Researchers report chromium and lead contamination in an Indian river and show that the aquatic fern Azolla pinnata can reduce ...
Manganese in Development Leaves Lasting Genomic Scars in Flies, While Quercetin Shields Them
Developmental manganese exposure leaves fruit flies with persistent oxidative stress, DNA fragmentation and protein glycation in adulthood, while early quercetin ...
Hidden zinc finger protein gives tomato wilt fungus its killer edge, study reveals
A Fusarium-specific transcription factor called FolSrz1 enables the tomato wilt fungus to resist oxidative stress and cause disease by maintaining ...
Cigarette Smoke Disrupts Mitochondria in Airway Cells but Leaves Mitochondrial DNA Methylation Largely Untouched
New research shows cigarette smoke extract impairs mitochondrial respiration and transiently boosts mitochondrial gene expression in airway cells without significantly ...
Bee Propolis Shields the Gut From Inflammatory Damage, Mouse Study Finds
A new mouse study shows that propolis protects against LPS-induced intestinal injury by reducing inflammation, boosting antioxidant defenses, reinforcing the ...
Sleep Loss Rewires How Tramadol Acts on the Adolescent Brain
A new rat study finds that sleep deprivation reshapes the neurobiological effects of tramadol in the adolescent brain, altering lipid ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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