Inhibiting Aquaporin-4 Alleviates Ischemia-Reperfusion Brain Injury in Mice
In a mouse model of stroke, pharmacological inhibition of aquaporin-4 was associated with reduced brain damage and modulated markers of ...
Tag: Oxidative stress
Bilirubin Mediates Link Between Obesity and Telomere Shortening
A cross-sectional study of 6,717 US adults finds that serum total bilirubin statistically mediates 13.2% of the association between obesity ...
Novel Sulfur Nanoparticles Show Preventive and Therapeutic Promise in Rat Liver Cancer Models
Researchers have demonstrated that an oral sulfur nanoparticle formulation prepared in olive oil safely reduces tumor progression and markers of ...
Early‐Life Polyethylene Microplastic Exposure Exacerbates ADHD‐Like Behaviors in Mice via PI3K/AKT1/Nrf2 Signaling: Evidence From the Pilot Cohort and Multi‐Omics Analyses
A study in Advanced Science links early-life polyethylene microplastic exposure to worsened ADHD-like behaviors in mice via PI3K/AKT1/Nrf2 signaling, supported ...
Nutritional Deprivation Rapidly Alters Honeybee Metabolism and Downregulates Vital Stress Genes
A laboratory study reveals that water and food deprivation rapidly alter antioxidant enzymes and downregulate Hsp70 gene expression in worker ...
Computational and Cellular Study Links Air Pollutants to NOS2 in Depression
Researchers identified nitric oxide synthase 2 as a possible molecular link between air pollutant exposure and biological pathways implicated in ...
Mitochondrial uncoupler BAM15 shields mice from acute lung injury by calming STING inflammation
In a mouse study, the mitochondrial uncoupler BAM15 improved survival and eased lipopolysaccharide-induced acute lung injury by preserving mitochondrial integrity, ...
SGLT2 Induction in Vascular Cells May Drive Cardiovascular Dysfunction
A review in Cardiovascular Diabetology suggests that inducible SGLT2 expression in vascular tissues may drive endothelial dysfunction and amplify cardiovascular ...
Micro- and Nano-plastics May Reshape Cell Mechanics and Disrupt Hydrogen Sulfide Signaling
A new review argues that micro- and nano-plastics may damage cells not only biochemically but by altering the mechanical properties ...
PTGS1 Silencing Boosts M2 Macrophages to Ease Prostatitis
A study in the Journal of Cellular and Molecular Medicine reveals that silencing PTGS1 promotes M2 macrophage polarization via PPARγ ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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