Tag: organoids

A two-stage culture system expanded mouse hepatocytes and produced organoids with partial recovery of hepatic metabolism, zonation-related responses and urea ...

Hundreds of patient-derived cancer models expanded dependency mapping and revealed vulnerabilities linked to mutations, cellular states and treatment history, while ...

A mouse organoid system shows that defined signals can separately initiate acinar-to-ductal conversion, sustain metaplastic expansion and promote partial redifferentiation ...

Researchers at Kumamoto University report that high salt tonicity, acting through the transcription factor NFAT5, drives the morphological, transcriptional, and ...

A new review maps how patient-derived induced pluripotent stem cells and three-dimensional vascular and neurovascular organoids are transforming Moyamoya disease ...

Patient-derived microtumors grown from core needle biopsies as small as a few cubic millimeters of tissue successfully predicted breast cancer ...

The UC Davis NAMs Testing Center offers an independent, fit-for-purpose evaluation model for organoids, microphysiological systems and computational tools as ...

A single letter change in a protein that shepherds RNA through the splicing machinery may be enough to rewire thousands ...

A new review details how tissue engineering, 3D bioprinting, tissue chips, and biosensors are turning orbital microgravity into a powerful ...

Researchers at Tufts University and Boston University report that low-dose mixtures of common bisphenols can disrupt normal breast development in ...