Nerve Signal Neuromedin U Shields Aggressive Prostate Cancer From Immune Attack
Wistar Institute researchers found that the neurotransmitter neuromedin U suppresses T cell infiltration at the earliest stage of neuroendocrine prostate ...
Tag: oncogene
RDM1 Emerges as a Master Switch Linking DNA Repair and Antioxidant Defense in Head and Neck Cancer
New research reveals that RDM1, a cytoplasmic protein with a RAD52 motif, acts as an oncogenic driver in head and ...
Cancer Gene Mutations Awaken the Immune System in Early Oral Cancer
Researchers at Tokushima University found that combined TP53 and CDKN2A mutations activate cGAS–STING-mediated antitumor immunity, delaying progression to invasive oral ...
One Cancer Gene, Two Fates: Study Shows Senescent Cells Split Into Tumor Blockers and Tumor Seeds
An NYU Abu Dhabi study in EMBO Reports shows that a single cancer-causing gene drives liver cells into distinct senescent ...
Beyond the On-Off Switch: Chemical Tags on KRAS Reshape Cancer Drug Design
A new review in Advanced Cancer Research details how post-translational modifications regulate KRAS localization, activity, stability, and degradation, opening fresh ...
Virus-driven lymphoma cells rely on a mitochondrial enzyme duo to dodge cell death
New research reveals that the mitochondrial ubiquitin ligase MARCHF5 helps KSHV-transformed lymphoma cells survive by degrading NOXA, the natural antagonist ...
RNA-Binding RBM Proteins Emerge as Double-Edged Players in Cancer
A new review in Medical Oncology details how the RBM family of RNA-binding proteins acts as both tumor suppressors and ...
Two Cancer Genes Pull in Opposite Directions in Papillary Thyroid Tumors
A study of 125 papillary thyroid cancer patients finds that EGFR and GLI1 are both upregulated in tumors but inversely ...
Hidden DNA Rings and a Rogue Gene Reveal Ovarian Cancer’s Adaptive Defense
A new study links HDAC inhibitor treatment to remodeling of extrachromosomal circular DNA in ovarian cancer and identifies LMO2 as ...
Single RNA Letter Swap Turns a Thyroid microRNA From Tumor Suppressor Into Cancer Driver
Researchers show that ADAR2-mediated A-to-I RNA editing switches miR-376a-3p from a tumor suppressor to an oncogene in papillary thyroid cancer ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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