Single phosphorylation event controls where NMDA receptors sit in the brain
A new Nature Neuroscience study shows that SIK3 phosphorylates GluN1 at a single site to control the recruitment of NMDA ...
Tag: NMDA receptors
Research report: Local circuitry mechanisms underlying motor cortex stimulation for chronic pain treatment
A BMC Medicine review proposes that motor cortex stimulation can relieve specific chronic pain conditions through local excitation, inhibition, and ...
NMDA receptors play an important role in postictal potentiation in immature rats
Neonatal seizures remain one of the most stubborn challenges in clinical neurology. The highest prevalence of seizures in humans occurs ...
How to train your neuron: building a detailed, up-to-date, multipurpose model of hippocampal CA1 pyramidal cells
Researchers have built and validated a new general-purpose biophysical model of hippocampal CA1 pyramidal neurons that captures a wide range ...
New AI Pipeline Watches Tens of Thousands of Synapses Fire at Once
Researchers in Berlin have developed an automated calcium imaging pipeline that detects and quantifies activity across tens of thousands of ...
Hippocampal GluN2A Knockdown Differentially Alters Spatial Exploration and Behavioral Performance in Male and Female Rats
A new study shows that selectively reducing the GluN2A subunit of NMDA receptors in the adult hippocampus disrupts spatial exploration ...
Human Brain Tissue Reveals a Cortex Built on Different Rules Than Rodents
A new collection of studies using live human cortical tissue shows that human neurons and circuits follow distinct structural, physiological, ...
Silent Synapses Wake Up: How Dormant Brain Connections Could Reshape Treatment of Disease
A sweeping review reveals how dormant silent synapses are activated through coordinated molecular machinery, and how their failure or overactivation ...
Flash EEG Test Reveals Hidden Visual Brain Deficits Behind Schizophrenia Cognition
A new multimodal EEG and fMRI study shows that simple flashing lights can expose deficits in the magnocellular and koniocellular ...
Ketamine Plus Midazolam May Soften Psychiatric Fallout After Vascular Surgery
A large database study finds that vascular surgery patients given ketamine alone faced roughly doubled odds of new psychiatric diagnoses ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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