Bioprinted Coronary Artery Model Recreates Kawasaki Disease in the Lab
A 3D bioprinted human coronary artery equivalent reproduces Kawasaki disease vasculitis using patient serum and enables rapid drug screening.
Tag: NLRP3
Vitamin D’s Active Form Triggers Cell Death and Rewires Purinergic Signaling in Melanoma Cells
A new study shows that calcitriol, the active form of vitamin D, kills A375 melanoma cells through mitochondrial dysfunction and ...
Innate Immune Sensors in Focus: Structural Insights into Inflammasomes and PANoptosomes Open New Therapeutic Avenues
A Cell Research review synthesizes structural and mechanistic insights into inflammasomes and PANoptosomes, revealing how innate immune sensors assemble inflammatory ...
Autophagy Protein AMBRA1 Unlocks NLRP3 Inflammasome Activation
Researchers have discovered that the autophagy protein AMBRA1 directly binds and allosterically opens the autoinhibited NLRP3 inflammasome, revealing a new ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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