Peptide and Trace Element Team Up Against Diabetic Ulcers, Review Finds
A new review outlines how the regenerative peptide thymosin beta 4 and the trace element selenium could work synergistically across ...
Tag: NF-kB
Bioprinted Coronary Artery Model Recreates Kawasaki Disease in the Lab
A 3D bioprinted human coronary artery equivalent reproduces Kawasaki disease vasculitis using patient serum and enables rapid drug screening.
Two Coumarins From Korean Angelica Root Carry Most of Its Anti-Inflammatory Power
A new study shows that the two pyranocoumarins decursin and decursinol angelate reproduce the major anti-inflammatory and antioxidant effects of ...
SIRT1 Emerges as a Plausible Molecular Link Between Bone Marrow Edema and Bone Remodeling
A new review synthesizes evidence that the NAD+-dependent deacetylase SIRT1, a master regulator of bone remodeling, may also influence bone ...
Radiotherapy Backfires: PD-1-Positive Monocytes Emerge as Hidden Drivers of Treatment Resistance
New research reveals that radiotherapy induces PD-1 expression on tumor-associated monocytes through an adenosine-driven signaling pathway, creating an immunosuppressive cell ...
Heat Stress Rewires Gut Microbes to Fuel Inflammation, and Arginine May Dampen the Fire
A new Microbiome study shows heat stress disrupts gut microbes to raise LPS and deplete arginine, amplifying MyD88-driven inflammation, and ...
Scientists uncover a hidden protein driver of sepsis-related organ failure
New research shows that the protein IGFBP7 drives sepsis-induced multiple organ failure by binding the mitochondrial enzyme OGDH, boosting its ...
Aging Muscle Weakens When a Key Exercise Enzyme Stays Switched On
New research in Aging Cell shows that the exercise-responsive enzyme CaMKII, when chronically activated, drives mitochondrial mislocalization, aging-like gene expression, ...
Ancient Chinese Herb Compound Gastrodin Reawakens Exhausted T Cells to Fight Leukemia
New research shows that gastrodin, a compound from the traditional Chinese medicine herb Gastrodia elata, restores T cell receptor signaling ...
Signaling Antagonism Helps Macrophages Identify Threats in Complex Ligand Mixtures
A combination of mathematical modeling and live-cell imaging shows that competition between signaling pathways, rather than hindering immune detection, actually ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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