Modified Dioscorea Pills improve cognition in rat cerebral hypoperfusion model
A 14-herb Chinese medicine improved learning and memory and altered hippocampal injury and vascular markers in rats with experimentally induced ...
Tag: neurovascular unit
Patient-derived stem cells and organoids open a new window on Moyamoya disease
A new review maps how patient-derived induced pluripotent stem cells and three-dimensional vascular and neurovascular organoids are transforming Moyamoya disease ...
Inflammatory receptor GPR84 weakens the blood-brain barrier after stroke, study finds
New research identifies the inflammatory receptor GPR84 as a driver of blood-brain barrier breakdown after ischemic stroke through a cAMP-CREB ...
Mitochondrial Metabolic Remodeling Drives Blood–Brain Barrier Dysfunction After Repetitive Mild Traumatic Brain Injury
A new review argues that recurrent mitochondrial metabolic stress, redox imbalance, and inflammatory signaling converge on the neurovascular unit to ...
ApoE4 May Raise Risk of Cognitive Decline From Small Vessel Disease, Review Finds
A new narrative review argues that ApoE4 acts as a context-dependent susceptibility modifier in cerebral small vessel disease rather than ...
Astrocyte Enzyme PHGDH Drives Blood Vessel Repair After Stroke
New research shows that the astrocytic enzyme PHGDH supplies serine to growing brain vessels through endothelial SLC38A2 transport and mTORC1 ...
Lab-Grown Brain Tumor Organoids Build Their Own Blood Vessels and Scaffolding
Researchers have grown glioblastoma organoids without any exogenous scaffold, allowing tumor stem cells to autonomously assemble neurovascular-like structures and extracellular ...
Huntington’s Disease Damages Brain Arterioles, but S1PR1 Stimulation Offers Reversal
A new Nature Communications study shows that Huntington's disease damages brain arterioles in a barrier-type-selective pattern coupled to reactive astrogliosis, ...
Astrocyte Fibronectin Emerges as Key Driver of Blood–Brain Barrier Failure in Alzheimer’s Disease
A new Nature Aging study identifies astrocyte-derived fibronectin as the molecular link between the APOE ε4 allele, amyloid pathology, and ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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