Ultrasound and Light Guide Gene Editing to Selected Sites in Mouse Brains
A light-sensitive Cas12f editor and ultrasound-triggered nanoparticles enabled researchers to control gene disruption at a selected location in mouse brains.
Tag: Neuroscience
New AI Model Learns a Generative Map of EEG Microstates While Preserving Their Spatial Shape
A new convolutional variational deep embedding model learns a generative latent manifold of EEG microstate topographies, offering soft cluster assignments ...
Prefrontal cortex activity fails to predict how well individuals regulate emotions, Nature study finds
An international fMRI analysis of 2,175 people across 40 studies found that prefrontal cortex activity during cognitive reappraisal does not ...
Lightweight Dual-Branch AI Reads Brain Scans to Spot Alzheimer’s Stages
A lightweight dual-branch AI framework called NeuroCST classified Alzheimer's disease stages from MRI scans with 98.42 percent accuracy while using ...
Reanalysis of Public Electron Microscopy Data Reveals Umbelliferone’s Effects on Synaptic Structure
A reanalysis of a public electron microscopy dataset found that umbelliferone increased postsynaptic density length and width compared with scopolamine ...
New microscopy method reaches 2-mm-deep neuronal imaging in the mouse brain
A new three-photon imaging system called TrUDI achieves cellular-resolution recordings of neuronal population activity at depths of up to about ...
Four Simulation Tools Put Astrocyte Calcium Signaling to the Test
A systematic comparison shows four neuroscience simulation tools produce consistent calcium reaction–diffusion results, while astrocyte branchlet geometry strongly shapes signaling.
Single phosphorylation event controls where NMDA receptors sit in the brain
A new Nature Neuroscience study shows that SIK3 phosphorylates GluN1 at a single site to control the recruitment of NMDA ...
Astrocyte Subtype Marked by CD51 Drives Synapse Formation and Stroke Recovery in Mice
A new mouse tool reveals that CD51-positive astrocytes are a functionally distinct subpopulation that promotes cortical synapse formation, hippocampal circuit ...
High-frequency sensory signals get stuck in the thalamus before reaching the cortex
A rat study combining fMRI, optogenetics, and connectivity modeling shows that high-frequency thalamic activation is preserved locally but fails to ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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