Oyster fungus yields new anti-inflammatory molecules that block nitric oxide enzyme
Scientists isolated three novel cytochalasins from an oyster-derived fungus, with two compounds curbing nitric oxide production in mouse microglial cells.
Tag: neuroinflammation
Swallowable magnetic particles stimulate the vagus nerve to ease Parkinson’s symptoms in mice
A capsaicin-coated magnetoelectric particle that generates electrical pulses in the stomach stimulated the vagus nerve and eased motor symptoms and ...
Repeated Histamine Exposure Shows Lasting Glial Changes and Attenuated Dopaminergic Deficits in Mice
Repeated peripheral histamine injections in mice were associated with persistent, region-specific glial morphometric remodelling and attenuated behavioural and dopaminergic deficits ...
RACK1 Loss Drives Neuronal Necroptosis in Mouse Sepsis Brain Study
A new Cell & Bioscience study in mice shows that downregulated hippocampal RACK1 potentiates LPS-induced neuronal necroptosis through the RACK1/RIPK1 ...
Thymoquinone eases postoperative pain in rats by calming spinal oxidative, inflammatory and apoptotic pathways
In a rat model of postsurgical pain, oral and intrathecal thymoquinone normalized incision-induced mechanical allodynia and modulated spinal oxidative, inflammatory ...
Kynurenine pathway imbalance may drive seizures and depression in epilepsy
A narrative review links an imbalance between kynurenic acid and quinolinic acid in the kynurenine pathway to seizures, drug resistance ...
Vagus Nerve Stimulation Curbs Amyloid Buildup After Surgery in Mice With Alzheimer-Like Disease
In Alzheimer-model mice, minimally invasive vagus nerve stimulation delivered right after orthopedic surgery reduced acute amyloid-beta accumulation, neuronal loss and ...
Gut, Immune and Brain Signals May Link COVID-19 to Parkinson’s Risk
A new review argues that gut dysbiosis, immune hyperactivation and HPA axis disruption link idiopathic Parkinson's disease with the systemic ...
Choroid plexus emerges as key player in multiple sclerosis progression, systematic review finds
A systematic review synthesises preclinical and human evidence that the choroid plexus drives immune infiltration, barrier disruption and genomic changes ...
LncRNA AK158273 curbs microglial autophagy via Mst1 in LPS neuroinflammation model
A new study reports that lncR-AK158273 suppresses microglial autophagy during LPS-induced neuroinflammation by upregulating Mst1 expression.
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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