Glycolysis enzymes emerge as central players in Alzheimer’s brain energy failure
A new review argues that dysregulated glycolytic and pyruvate-metabolizing enzymes in specific brain cell types form a central axis linking ...
Tag: neuroinflammation
Microglial NLRP3 Inhibition Restores Memory After Hemorrhagic Shock in Mice
A mouse study finds that inhibiting the NLRP3 inflammasome specifically in microglia reduces hippocampal neuroinflammation and reverses cognitive deficits after ...
Retina’s Master Support Cells Take Center Stage in Blinding Disease
A new review argues that Müller glia, the retina's dominant support cells, actively shape retinal disease progression and may offer ...
Plant Compound Ivangustin Pins Neuroinflammation on Covalent Hit at UBE2L3 Cys86
A new study reports that ivangustin, a sesquiterpene lactone from Inula japonica, suppresses microglial NF-κB signaling by covalently modifying cysteine ...
From PTZ to Brain Organoids: How Scientists Choose the Right Epilepsy Model
A new review maps how chemical, electrical, genetic, acquired, and in vitro epilepsy models each capture distinct mechanisms of epileptogenesis, ...
Loss of CD47 Shifts Mouse Hippocampus Toward a Mild Stress-Like State
Single-nucleus RNA sequencing shows that Cd47 loss shifts the mouse hippocampal transcriptome toward a state resembling mild excitotoxic stress.
Research report: Fulminant pancreatic encephalopathy with brain edema and herniation in severe hypertriglyceridemia-induced pancreatitis: a case report
A 23-year-old woman with insulin resistance and severe obesity arrived at an emergency department in Beirut with severe upper abdominal ...
Chitosan Nanoparticles in GelMA Hydrogel Deliver Resveratrol in pH-Responsive Manner In Vitro
An in vitro study reports a chitosan nanoparticle and GelMA hydrogel platform that releases resveratrol faster at acidic pH and ...
When Do Repeated Concussions Stop Being Transient? New Research Topic Weighs In
A new Frontiers in Neurology editorial argues that symptom resolution may mask persistent biological changes after repeated concussions.
Stroke begins years earlier: vascular dysfunction offers a window for prevention
A new review argues that stroke is the endpoint of progressive vascular failure and that translational models can uncover biomarkers ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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