Elevated Stool Amyloid and Tau Aggregates Distinguish Individuals With Cognitive Impairment
A clinical study shows that amyloid-beta and tau aggregates are detectable in human stool and significantly elevated in individuals with ...
Tag: neurodegenerative disease
Machine Learning Identifies Three ALS Progression Patterns
A new machine learning framework identifies three distinct progression patterns in ALS patients, offering a tool for earlier prognostic assessment ...
Pilot Study Links Environmental Factors to Lewy Body Dementia Risk
An exploratory remote pilot study found that metal exposure, alcohol, and smoking were associated with higher Lewy body dementia risk, ...
Algerian Parkinson’s Study Identifies Rare Variants in Six Candidate Genes
An exploratory study of 19 Algerian patients with Parkinson’s disease identified rare variants in six candidate genes, highlighting the genetic ...
Deep Cervical Lymph Node Size May Track Parkinson’s Disease Severity
In a small exploratory study, Parkinson's disease patients had smaller deep cervical lymph nodes than healthy controls, and node measurements ...
SEL1L emerges as a molecular gatekeeper of cellular protein quality control
A systematic review links the SEL1L-HRD1 quality control complex to neurodegeneration, cancer, metabolism and immunity.
Inflammatory stimulation reshapes microglial vesicle miRNA cargo and modestly alters recipient cells
An in vitro study found that LPS-stimulated microglia enriched miR-155 and increased miR-34a in donor cells and their extracellular vesicles, ...
Brain FDG PET Scan Flags Cognitive Decline Risk in Psychiatric Patients
A study of 34 psychiatric patients with confirmed cognitive symptoms found that brain FDG PET identified those at risk of ...
Small Molecule Strategy Degrades Many Disease Proteins at Once in Cell Models
A new small molecule strategy activates a stress-responsive E3 ligase to degrade multiple disease-causing proteins at once, restoring mitochondrial function ...
Parkinson’s Disease Raises Fracture Risk, and Osteoporosis Care Must Keep Up
A new perspective article argues that osteoporosis prevention deserves far more attention in people with Parkinson's disease, especially when dementia ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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