Review links microglial metabolism to adult neurogenesis regulation
A 2026 mini review concludes that microglial metabolic states may connect brain pathology with adult neurogenic niche remodeling through phagocytosis, ...
Tag: Neural Stem Cells
Landmark Study Linking Estrogen to Ketamine Brain Protection Retracted Over Image Integrity
Frontiers in Neuroscience has retracted a 2020 study claiming 17β-estradiol protects neural stem cells from ketamine injury after image integrity ...
New Protocol Keeps Living Brain Slices Alive for Weeks to Track Birth of New Neurons
Researchers have refined a decades-old method for keeping intact mouse hippocampal slices alive for weeks, enabling precise quantification of newborn ...
Oxygen Shapes the Developing Cortex, but HIF-2α Turns Out Not to Be the Messenger
A new mouse study shows that oxygen levels strongly influence cortical development, but the oxygen sensor HIF-2α is not the ...
Stem Cell Enzyme PLA2G7 Emerges as a Driver of Age-Related Memory Decline
Researchers report that suppressing the lipid-metabolizing enzyme PLA2G7 in hippocampal neural stem cells restores inhibitory synapses and improves memory in ...
Master Switch Discovered That Decides How Adult Spinal Cord Stem Cells Choose Their Fate
New research reveals that the Hippo pathway effector YAP1 acts as a master switch controlling whether adult spinal cord stem ...
Aging Brains Respond Differently in Males and Females, Mouse Study Reveals
A new study in accelerated-aging mice shows that a neurogenesis-boosting compound rescues memory and hippocampal plasticity in males but not ...
Blood Cells From 80-Year-Olds Rejuvenated Into Brain Cells With Molecular Age Under 20
University of Bonn researchers directly reprogrammed red blood cell precursors from elderly donors into neural stem cells whose epigenetic clocks ...
Early-Life NAD+ Booster Shows Promise for Cognitive Deficits in Schizophrenia Model
A short course of the NAD+ precursor NMN given to young mice in a two-hit schizophrenia model was associated with ...
Blood Cells Rewound: Direct Neural Conversion Slowly Erases Epigenetic Age
Direct conversion of human blood cells into neural stem cells erases nearly all epigenetic age over a protracted fifty-day process ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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