Lipid Nanoparticles Reprogram NK Cells Inside the Body to Fight Cancer and Autoimmune Disease
MIT engineers have developed lipid nanoparticles that reprogram natural killer cells inside the body to destroy cancerous and autoreactive T ...
Tag: Nature Biotechnology
Proteomic Aging Clocks Face Their First Real-World Test in a Clinical Trial
For the first time, six proteomic aging clocks have been deployed as readouts in a clinical trial, revealing more about ...
Lipid nanoparticles reprogram natural killer cells inside the body to fight cancer
MIT researchers have engineered ligand-directed lipid nanoparticles that reprogram natural killer cells into CAR-bearing cancer killers directly inside living animals, ...
Flawed Benchmarks Hid AI Success in Gene Perturbation Prediction
A new calibration framework shows that common benchmarking metrics masked real perturbation-specific signal, and that deep learning models can outperform ...
AI Reads the Retina to Predict Preeclampsia Months Before Symptoms Appear
An interpretable AI platform that reads the retinal vasculature predicted preeclampsia and other hypertensive disorders of pregnancy months before clinical ...
Shotgun genetic engineering lets mammalian cells stumble onto new metabolic pathways
A Nature Biotechnology commentary highlights how shotgun genetic engineering, which tests vast random combinations of genes in mammalian cells, enabled ...
Shotgun genetic engineering lets mammalian cells test millions of designs at once
Researchers have developed shotgun genetic engineering, a multiplexed strategy that screens millions of combinatorial genetic designs in mammalian cells within ...
Bird-Derived Jumping Gene Rewritten to Insert DNA into Human Cells with RNA Alone
Researchers mined 1,139 avian genomes for R2 retrotransposons and engineered variants that achieve up to 60 percent site-specific, all-RNA-mediated gene ...
Detectrons Turn Fleeting RNA Signals into Lasting DNA Barcodes Inside Living Cells
Researchers have engineered Detectrons, toehold-switch biosensors coupled to retron reverse transcription, that convert specific RNA sequences inside living cells into ...
AI-Guided Design Yields mRNA Vaccines That Survive Months Without Refrigeration
MIT researchers used a data-efficient AI framework to discover solid-state mRNA–lipid nanoparticle vaccine formulations that retained full bioactivity after months ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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