AI-Guided Design Yields mRNA Vaccines That Survive Months Without Refrigeration
MIT researchers used a data-efficient AI framework to discover solid-state mRNA–lipid nanoparticle vaccine formulations that retained full bioactivity after months ...
Tag: Nature Biotechnology
Light-Patterned DNA Tags Give Single-Cell Sequencing a Sense of Place
A new light-based barcoding technique called scSTAMP-seq stamps spatial coordinates onto individual cells using photocleavable DNA tags, enabling joint transcriptomic ...
Common RT–qPCR Artifact May Inflate RNA Knockdown in CRISPR Experiments
New research shows that a pervasive RT–qPCR artifact can artificially inflate reported RNA knockdown by RNA-targeting CRISPR systems.
AI-Enhanced Adaptive Virtual Screening Accelerates Ligand Discovery in Huge Compound Libraries
An adaptive artificial intelligence framework slashes the computational cost of screening billion-molecule chemical libraries while experimentally confirming high-quality ligand hits ...
Engineered Landing Pads Boost Precision Gene Integration in Plants and Human Cells
Engineered genomic attachment sites dramatically increase the efficiency of site-specific DNA integration in both plant and human cells.
DartUniFrac Brings Megascale Computing to Microbiome Diversity Analysis
A new high-performance tool called DartUniFrac enables phylogenetic microbiome diversity analysis at unprecedented scale, overcoming the computational limits of classical ...
Engineered Bacteria Supercharge Rock Weathering to Pull Carbon from the Sky
Engineered bacteria that overproduce rock-dissolving siderophore molecules significantly accelerate silicate mineral weathering, potentially boosting carbon dioxide removal on farmland.
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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