Cellular Recycling Pathway Slows Aging by Keeping Senescent Cells in Check
Deep inside nearly every cell, a molecular cleanup crew works around the clock to keep the interior tidy. One of ...
Tag: Nature Aging
Stem Cell Enzyme PLA2G7 Emerges as a Driver of Age-Related Memory Decline
Researchers report that suppressing the lipid-metabolizing enzyme PLA2G7 in hippocampal neural stem cells restores inhibitory synapses and improves memory in ...
Chemical Tags on Brain DNA Reveal How Alzheimer’s Risk Genes Do Their Damage
A large postmortem study identified 107 brain DNA methylation sites linked to Alzheimer's pathology and showed that methylation partially mediates ...
Scientists uncover the molecular switch that reshapes aging muscle
University of Copenhagen researchers found that declining cardiolipin in mitochondria triggers an ERRĪ³-driven, ROS-mediated switch that trades muscle power for ...
How aging and sex reshape the immune system’s fight against cancer
A new Nature Aging study from Mass General Brigham shows that male and female immune systems age differently, with earlier ...
A Shrinking Thymus May Blunt Cancer Immunity in Middle-Aged Men
New research in Nature Aging shows that accelerated loss of naive CD8+ T cells in middle-aged male mice shrinks lymph ...
Oocytes Activated in Youth Can Persist for a Lifetime, Mouse Study Reveals
A lineage-tracing study in mice shows that oocytes activated early in life can persist for nearly the entire reproductive lifespan ...
A Fading Mitochondrial Fat May Drive the Way Aging Muscles Change Shape
New research shows that the age-related decline of the mitochondrial lipid cardiolipin causally drives the shift from fast glycolytic to ...
Longer Fat Chains, Shorter Lives: Lipid Elongation Emerges as a Hallmark of Aging
A Nature Aging commentary highlights research identifying lipid acyl-chain elongation as a conserved, causal and potentially reversible hallmark of aging ...
Exercise Sends Molecular Messages That Rejuvenate Aging Joint Cartilage
Mass General Brigham researchers report in Nature Aging that moderate exercise enriches blood-borne extracellular vesicles with microRNA-29, a signal that ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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