Tag: natural products

An integrated study of Liriope platyphylla root identifies 63 lipophilic compounds and shows antioxidant and anti-inflammatory effects in macrophage cells.

Scientists report that solanesol, a plant terpenoid from tobacco leaves, matched metformin's antidiabetic effects in mice at a forty-fold lower ...

Scientists report that bark extracts from the African tree Erythrina excelsa selectively killed breast cancer cells and dramatically reduced tumors ...

A computational screen of 698 plant compounds identified diosgenin as a stronger and safer binder of antiapoptotic Bcl-2 family proteins ...

An AI-driven screening pipeline identified the fungal sterol 5,6-epoxyergosterol as a selective LXRβ agonist that exploits the cholesterol dependency of ...

A new study finds that two salt marsh plants from India's Cuddalore coast, Suaeda maritima and Sesuvium portulacastrum, are rich ...

Researchers have finally identified the genes and enzymes that bacteria use to build the anticancer drug 5-azacytidine, revealing rare skeletal-editing ...

A diterpenoid-rich fraction prepared from the roots of the Turkish sage Salvia oligophylla induced programmed cell death in MCF-7 breast ...

A prenylated isoflavone from licorice root suppresses fat cell formation by downregulating key adipogenic regulators and activating AMPK signaling in ...

A computational study finds that the cyclic lipopeptide fengycin, encoded by biosynthetic gene clusters widely shared among marine bacteria, outperforms ...