Chemical Tags on RNA Hold the Switch That Decides Whether Cells Die of Iron
A comprehensive review maps how m6A RNA methylation regulates ferroptosis across cancer, cardiovascular, neurological and metabolic diseases, revealing new therapeutic ...
Tag: nanoparticle drug delivery
Nanoparticle Paclitaxel Boosts Immunotherapy Response in Advanced Lung Cancer Trial
A phase II trial found that nanoparticle polymeric micellar paclitaxel combined with carboplatin and sintilimab produced an objective response rate ...
Old Dye Meets Nanoparticles in a Two-Pronged Attack on Glioblastoma
Researchers have combined IR780-paclitaxel albumin nanoparticles with acriflavine-releasing hydrogels to simultaneously block hypoxia-inducible factor 1 and heat shock protein 70, ...
Iron-Dexamethasone Nanoparticles Calm Overactive Neutrophils in Acute Lung Injury
Researchers have engineered iron-dexamethasone nanoparticles that are selectively engulfed by neutrophils, calming acute lung inflammation in mice while avoiding the ...
Metal-Organic Framework Wrapper Makes Ceftazidime Potent Against Resistant Urinary Infections
Researchers have encapsulated the antibiotic ceftazidime in a ZIF-8 metal-organic framework nanocarrier that dramatically improves treatment of Pseudomonas aeruginosa urinary ...
Poly(2-oxazoline) Micelles Deliver Paclitaxel and Metronidazole for Dual Tumor Therapy
Cancer researchers have built a nanoscale drug-delivery system that attacks two problems inside certain tumors at once: malignant cells and ...
Amino Acid Residue-Guided Nanoparticle Targeting of Protein Cavities: Moving Beyond Size Complementarity
The landscape of drug discovery is being revolutionized by an unexpected frontier: targeting the intricate interfaces between proteins using nanoparticles. ...
Multifunctional Nanoparticles Enable Bimodal Image-Guided Phototherapy for Advanced Bladder Cancer Treatment
Bladder cancer remains one of the most formidable challenges in the field of oncology, particularly due to its high recurrence ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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