Mitochondrial Cleanup and a DNA Sensor May Team Up to Drive Stroke Inflammation
A new review maps how mitophagy and the cGAS–STING pathway may jointly regulate post-stroke neuroinflammation through leaking mitochondrial DNA, based ...
Tag: Nanomedicine
Disease Microenvironments May Reshape the Safety of Near-Infrared Theranostic Nanomaterials, Review Finds
A new review argues that tumor acidity, hypoxia, reactive oxygen species and microbial cues can fundamentally alter the degradation, activation ...
ROS-responsive nanoparticle pairs PARP inhibitor with DOT1L blocker to fire up antitumor immunity in ovarian cancer models
A ROS-responsive nanoparticle co-delivering a PARP inhibitor prodrug and a DOT1L inhibitor amplified DNA damage, activated cGAS-STING signaling and improved ...
Engineered vesicles deliver miR-204 to triple-negative breast cancer cells in preclinical tests
Researchers engineered GE11-targeted vesicles that delivered tumor-suppressive miR-204 into EGFR1-positive triple-negative breast cancer cells, inhibiting their growth in lab and ...
Gold nanoparticles under the laser: a review maps the road from clean synthesis to cancer theranostics
A new open-access review synthesizes how gold nanoparticles are made, why their shape dictates plasmonic heating, and what still blocks ...
Natural Compounds That Build Their Own Nanomedicines Take Aim at Cancer
A new review maps how natural active compounds can self-assemble into carrier-free nanostructures for cancer therapy, while flagging major translational ...
Nanoparticle-delivered Pt(IV) prodrug shows boosted killing of cisplatin-tolerant oral cancer cells in 3D models
A platinum(IV) prodrug covalently attached to mesoporous silica nanoparticles showed significantly greater cytotoxicity than cisplatin in patient-derived oral squamous cell ...
Biosensors and Nanorobots Converge Toward Closed-Loop Cancer Theranostics
A systematic analytical review maps how ultra-sensitive biosensors and programmable nanorobotic platforms are being combined into closed-loop cancer theranostic systems, ...
Magnetic nanoparticles steer doxorubicin toward triple-negative breast tumors
Hyaluronic acid-decorated, iron oxide-loaded PLGA nanoparticles guided by a pulsed electromagnetic field increased tumor accumulation of doxorubicin roughly 1.5-fold in ...
Oxygen-Generating Liposomes Boost Dual Light Therapy Against Hypoxic Glioma Cells in Lab Tests
A microfluidically fabricated liposome co-loaded with a copper phthalocyanine photosensitizer and catalase cut hypoxic C6 glioma cell viability to about ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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