COPD phenotypes show distinct blood immune signatures linked to lung cancer
A cross-sectional study of 64 subjects found that COPD with emphysema shows lowered HLA-DR activation on circulating antigen-presenting cells while ...
Tag: myeloid-derived suppressor cells
Immune Cells Turned Accomplices: How the Body’s Defenses Help Cancer Spread
A new narrative review in Frontiers in Oncology details how T cells, macrophages, neutrophils, B cells, NK cells, and dendritic ...
Genetic Study Links Iron-Cell Death Genes to Leukemia Risk via Immune Cells
A Mendelian randomization study finds that ferroptosis-related genes influence acute myeloid leukemia risk directly and indirectly through specific immune cell ...
Bibliometric Analysis Maps a Decade of MDSC Research in the Tumor Microenvironment
A bibliometric analysis of 5,967 publications maps a decade of MDSC research, identifying leading countries, institutions, authors, and emerging research ...
Tumor acidity emerges as a metabolic barrier blocking cancer immunotherapy
A narrative review argues that the acidic tumor microenvironment suppresses antitumor immunity and that targeting acidity is a preclinically supported ...
Bladder cancer immune landscape is compartmentalized, treatment-modified, and context dependent
A new narrative review finds that the clinical meaning of immune infiltration in bladder cancer depends on cell localization, functional ...
B7-H3 blockade and MEK inhibition overcome immune defenses in prostate cancer models
In preclinical castration-resistant prostate cancer models, combining B7-H3 blockade with the MEK inhibitor trametinib overcame compensatory immune suppression and structural ...
Research report: JAK-STAT signaling: a key mechanism of immune microenvironment remodeling in breast cancer and novel strategies for targeted therapy
A 2026 review finds that JAK-STAT signaling suppresses antitumor immunity in breast cancer, but mixed clinical trial results expose challenges ...
Retrospective blood protein models predict outcomes in 38 HPV16 cancer patients
A retrospective study of 38 patients with advanced HPV16-positive cancers linked baseline and early serum protein measurements to outcomes from ...
Myeloid drugs rarely prove immune conversion in solid tumors
A 2026 narrative review finds that most myeloid-directed cancer programs show target activity without proving immune conversion and proposes a ...
-
Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
-
University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
-
Bee body mass, pathogens and local climate influence heat tolerance
-
Researchers record first-ever images and data of a shark experiencing a boat strike
-
Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
Embark on a thrilling journey of discovery with Scienmag.com—your ultimate source for cutting-edge breakthroughs. Immerse yourself in a world where curiosity knows no limits and tomorrow’s possibilities become today’s reality!