CRISPR-based LAMP assays detect tuberculosis with high accuracy in early study
Two LAMP-CRISPR diagnostic pipelines for Mycobacterium tuberculosis reached a limit of detection of 10 copies per microlitre, with the Cas12a ...
Tag: Mycobacterium tuberculosis
Ecuador Study Reveals Ultra-Low Prevalence of a Drug-Resistant Beijing Tuberculosis Strain
A study analyzing 699 M. tuberculosis isolates from 2018 and 2023 in Ecuador found only one Beijing sublineage isolate, which ...
Drug-Resistant RDRio Tuberculosis Strain Tracked Across Ecuador
A surveillance study of 699 tuberculosis isolates from Ecuador found the drug-resistance-associated RDRio genotype at 5.72 percent prevalence, stable from ...
Whole-genome sequencing maps tuberculosis lineages and drug resistance across Indonesia
A national genomic survey of 1,281 Mycobacterium tuberculosis isolates reveals four major lineages, high isoniazid and rifampicin resistance, and the ...
Computational drug screening struggles against drug-resistant tuberculosis, review finds
A new review argues that virtual screening and AI-driven modeling have expanded the search for anti-tuberculosis drugs, but persistent mismatches ...
Larger Lymph Nodes and Pus Samples Boost Rapid TB Test Positivity in Neck Nodes
A retrospective study of 334 patients found that lymph nodes at least 1.5 centimeters wide and pus specimens were independently ...
Tuberculosis bacterium resists innate immune clearance in mouse models
Mouse infection experiments show that Mycobacterium tuberculosis remains difficult for innate immunity to clear across ultra-low-dose, microbiota-primed, and Legionella-primed models.
Retrospective Ethiopian hospital study finds no detectable five-year TB trend
A retrospective analysis of 4,351 Ethiopian hospital records found no statistically significant five-year trend in MTB detection or rifampicin resistance, ...
Phage screening identifies candidate tuberculosis peptides for HLA-E
A phage-display and computational screen prioritized 14 Mycobacterium tuberculosis fragments as candidate HLA-E ligands, but experimental validation is still required.
Iraqi pre-XDR tuberculosis strains reveal diverse lineages and resistance mutations
Whole-genome analysis of two Iraqi pre-XDR tuberculosis isolates identified distinct lineages, established drug-resistance mutations and differences in genes associated with ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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