Low-Dose BCMA CAR-T Therapy Anito-Cel Eradicates Myeloma in All 38 Phase 1 Patients
A phase 1 trial found that the investigational BCMA-targeted CAR-T therapy anito-cel produced responses in all 38 participants with relapsed ...
Tag: Multiple Myeloma
Proteasome Inhibitors Fail to Show Measurable Bone and Quality-of-Life Benefits in Myeloma Patients
A prospective real-world cohort study finds that proteasome inhibitor-based therapy is not associated with measurable differences in quality of life, ...
Chromatin Structure and DNA Repair Shaped a Multiple Myeloma Chemotherapy Study Now Retracted
The British Journal of Cancer has retracted a 2014 study linking chromatin structure and DNA repair to chemotherapy outcomes in ...
Myeloma Drug Pomalidomide Halts Severe Nosebleeds in Inherited Vascular Disease
A Japanese case report describes how the myeloma drug pomalidomide rapidly relieved transfusion-dependent nosebleeds in a patient with hereditary hemorrhagic ...
Neutrophils Fail Quietly in Multiple Myeloma Even When Counts Look Normal
A study of Zambian multiple myeloma patients shows their neutrophils have severely impaired phagocytosis and oxidative burst despite normal blood ...
Hidden Metabolic Trick Lets Myeloma Cells Steal Fuel to Survive a Key Cancer Drug
New research reveals that resistant myeloma cells import putrescine through the transporter SLC45A4, activating HOXA1-driven NF-kappaB signaling with help from ...
From Ancient Rocks to Cancer Wards: Stable Isotopes Emerge as Mechanistic Biomarkers
A new review argues that stable isotope fractionation patterns, long used to reconstruct Earth's history, could become mechanistic biomarkers for ...
Rare Skin Disease Pityriasis Rubra Pilaris Linked to Higher Odds of Leukemia and Lymphoma
A large matched cohort study using U.S. electronic health records finds that patients with pityriasis rubra pilaris have significantly higher ...
Same Struggles, Different Reasons: Patients and Caregivers Walk Parallel Paths in Multiple Myeloma
A paired study of 44 multiple myeloma patient-caregiver dyads in Seoul finds that patients and caregivers face nearly identical life ...
Real-World Data Show Carfilzomib Regimens Deliver Strong Results in Multiple Myeloma
The final results of the German CARO study show that carfilzomib-based regimens achieve high adherence, trial-consistent effectiveness, and stable quality ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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