Hidden Metabolic Trick Lets Myeloma Cells Steal Fuel to Survive a Key Cancer Drug
New research reveals that resistant myeloma cells import putrescine through the transporter SLC45A4, activating HOXA1-driven NF-kappaB signaling with help from ...
Tag: Multiple Myeloma
From Ancient Rocks to Cancer Wards: Stable Isotopes Emerge as Mechanistic Biomarkers
A new review argues that stable isotope fractionation patterns, long used to reconstruct Earth's history, could become mechanistic biomarkers for ...
Rare Skin Disease Pityriasis Rubra Pilaris Linked to Higher Odds of Leukemia and Lymphoma
A large matched cohort study using U.S. electronic health records finds that patients with pityriasis rubra pilaris have significantly higher ...
Same Struggles, Different Reasons: Patients and Caregivers Walk Parallel Paths in Multiple Myeloma
A paired study of 44 multiple myeloma patient-caregiver dyads in Seoul finds that patients and caregivers face nearly identical life ...
Real-World Data Show Carfilzomib Regimens Deliver Strong Results in Multiple Myeloma
The final results of the German CARO study show that carfilzomib-based regimens achieve high adherence, trial-consistent effectiveness, and stable quality ...
Taste Loss From a Breakthrough Myeloma Drug May Push Patients to Quit Therapy
A cross-sectional study of 32 multiple myeloma patients found that talquetamab caused taste disturbances in every participant, with impaired taste ...
One in three older Americans learns they have myeloma in the emergency room
A SEER-Medicare analysis of 20,437 older adults found that 37 percent of multiple myeloma diagnoses occurred through emergency department involvement, ...
Stem Cell Transplant Deepens Myeloma Response, and a Year of MRD Negativity May Signal Lasting Remission
A real-world study of fifty multiple myeloma patients found that high-dose melphalan with autologous stem cell transplantation doubled complete response ...
Myeloma Patients Crave Breaks From Treatment but Keep Their Check-Ups
A survey of 100 multiple myeloma patients in Germany finds that nearly half highly value treatment-free intervals for recovery, yet ...
Mass spectrometry screening reveals high MGUS prevalence among Black South Africans in Soweto
The largest MGUS screening study in sub-Saharan Africa found that roughly 15 percent of Black South Africans in Soweto carry ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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