Cell assays and molecular modeling assess 1,2,3-thiadiazole derivatives against cancer cell lines
A cell-based and computational study found compound 5g had the highest measured cytotoxic activity in most tested cancer cell lines ...
Tag: MTT assay
Piper betle leaf oil shows cell cytotoxicity and antioxidant activity in vitro
An in vitro study found antioxidant activity in four assays and concentration-dependent cytotoxicity against KB oral carcinoma cells, with an ...
Oxadiazole compound shows potent selectivity against oligodendroglioma cells
Researchers have synthesized a series of 1,3,4-oxadiazole derivatives and evaluated their anticancer potential against HS683 human oligodendroglioma cells, identifying one ...
Metal Meets Molecule: How Schiff Base Chelates Are Emerging as Antimicrobial and Anticancer Powerhouses
A new review in Discover Chemistry surveys how Schiff base metal complexes of cobalt, copper, zinc, platinum and other metals ...
Bee Venom Enzyme Shows Potent Activity Against Leishmania Parasites in Lab Tests
A new in vitro study reports that purified honey bee venom phospholipase A2 inhibits Leishmania major parasites at concentrations significantly ...
Oyster Mushroom Extract Shows Potent Anticancer Activity Against Breast Cancer Cells
A methanolic extract of the edible oyster mushroom Pleurotus eous showed strong antioxidant activity and dose-dependent cytotoxicity against MCF-7 breast ...
Lychee Seed Extract Shows Promise for Healing Oral Wounds in Lab Study
A crude extract from discarded lychee seeds proved non-toxic to human gum fibroblasts at low doses and boosted cell proliferation ...
Chlorine Position Decides Which Oxadiazole Molecules Kill Breast Cancer Cells
Chemists have designed nine 1,3,4-oxadiazole derivatives that inhibit breast cancer cells in vitro, with the lead compound R3 showing an ...
Hybrid Pyrimidine–Oxadiazole Molecules Show Striking Potency Against Cancer Cells
Chemists have fused pyrimidine and 1,3,4-oxadiazole rings into a new family of hybrid molecules, and the best member kills breast, ...
Common Antibiotic Blunts the Power of a Brain Cancer Drug in Cell Studies
New cell culture research shows that the widely used antibiotic cefazolin can weaken the anticancer effects of irinotecan in glioblastoma ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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