Tag: molecular docking

Researchers repurposed the approved drugs talazoparib, tivozanib and isradipine as candidate inhibitors of VAV2 signaling that reduced oxidized LDL uptake ...

A new study combines UPLC-MS/MS, network pharmacology, and animal experiments to show how the 800-year-old Chinese formula Danggui Buxue Decoction ...

Researchers used virtual drug repurposing to identify FDA-approved antibiotics Carbenicillin and Ceforanide as inhibitors of the β-catenin/Tcf4 interaction, showing anti-proliferative ...

An integrated study of Liriope platyphylla root identifies 63 lipophilic compounds and shows antioxidant and anti-inflammatory effects in macrophage cells.

A new review outlines how aptamer-guided nanocarriers could finally deliver CRISPR-Cas9 gene editing specifically to tumor cells, integrating molecular targeting, ...

A new computational study shows that adding graphene oxide to hydroxyapatite coatings substantially strengthens predicted binding to bone-building proteins and ...

Bioactive compounds from the medicinal tree Pistacia integerrima suppress the growth and migration of lung cancer cells by targeting PI3K, ...

A network-based study finds that the antiparasitic drug praziquantel alleviates liver fibrosis by targeting the estrogen receptor gene ESR1 in ...

An integrated computational and animal study shows that the soy isoflavone genistein targets five key genes to simultaneously lower blood ...

Researchers have used immunoinformatics and reverse vaccinology to design a multi-epitope mRNA vaccine candidate against Trypanosoma brucei, the parasite that ...