D-mannose inhibits triple-negative breast cancer via specific molecular axis
A new study reveals that D-mannose suppresses triple-negative breast cancer progression by modulating the miR-2116-3p/BAP1/KLF5 molecular axis.
Tag: Molecular Biology
Smurf1 Knockdown Drives Liver Failure via Ferroptosis
A new study reveals that knocking down the protein Smurf1 promotes ferroptosis in acute liver failure by stabilizing Ulk1 and ...
Review Evaluates Known and Emerging Inflammatory Biomarkers in Obstructive Sleep Apnea
A comprehensive scientific review outlines the clinical and diagnostic potential of established and novel inflammatory biomarkers in obstructive sleep apnea.
Ring-shaped protein caught on video grabbing and bundling DNA strands
High-speed atomic force microscopy has revealed how the Smc5/6 protein complex changes shape, captures DNA and tethers separate DNA strands ...
LCE3D Inhibits TGF-β1 to Drive Atopic Dermatitis Inflammation
A new study reveals that LCE3D promotes atopic dermatitis inflammation by inhibiting TGF-β1, identifying a potential therapeutic target.
DDX41 Gene Variants Linked to Severe Retinal Dystrophy
A new study in Genome Medicine identifies biallelic DDX41 variants as a cause of severe retinal dystrophy, expanding the known ...
Discrete Oxidized Carbon Nanotubes Enable Efficient Plasmid Transfection with Low Toxicity
Researchers demonstrated that discrete oxidized multi-walled carbon nanotubes coated with dual surfactants achieve plasmid transfection comparable to commercial lipid reagents ...
Large-Scale Screen Uncovers RNA-Binding Proteins Controlling Circular RNA Biogenesis and Translation
Researchers systematically evaluated 730 RNA-binding proteins using a tethered reporter assay, uncovering widespread regulators of circular RNA biogenesis, nuclear export, ...
Research report: 35-minute protocol for high-yield RNA extraction from gram-positive & gram-negative bacteria at room temperature without toxic chemicals
A modified acidic lysis protocol extracts intact RNA from Gram-positive and Gram-negative bacteria in 35 minutes at room temperature without ...
Optimized Asymmetric PCR Protocol Boosts Single-Stranded DNA Production for Aptamer Screening
An optimized two-step asymmetric PCR protocol improves the yield and purity of single-stranded DNA used in SELEX aptamer screening.
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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