AI Maps Whole Gene Networks That Cancers Cannot Live Without
A machine learning framework called BioBombe maps the biological processes that cancers depend on for survival, revealing new vulnerabilities and ...
Tag: mitochondrial metabolism
Sheep Skin Genes Reveal Hidden Biology Behind Black and White Coats
RNA sequencing of black and white Hortobágyi Racka sheep reveals that coat color differences extend beyond pigment genes into ion ...
Coumarin Supercharges Natural Killer Cells to Fight Liver Cancer, Study Finds
New preclinical research shows that the plant compound coumarin activates natural killer cells, boosts their mitochondrial energy supply, and shrinks ...
Scientists Zero In on Mitochondrial Genes Linked to Major Depression
An integrative bioinformatics and RT-qPCR study nominates ALDH3B1 and ALOX15B as preliminary mitochondrial metabolism-related candidate genes in major depressive disorder.
Engineered vaccinia virus GC001 shows potent tumour killing and clean safety profile
A thymidine kinase-deleted oncolytic vaccinia virus engineered to silence STRIP1 shows broad anti-tumour activity, ROS-Hippo pathway synergy and a clean ...
Higher Body Weight Linked to Lower Brain Cell Health Marker, Meta-Analysis Finds
A meta-analysis of 23 spectroscopy studies finds that higher body mass index is consistently associated with lower concentrations of the ...
Astragaloside IV Shows Cardioprotective Metabolic Effects in Diabetic Heart Cells
A multi-omics study shows that astragaloside IV protects heart cells from high-glucose injury by remodeling TCA cycle metabolites and mitochondrial ...
Copper and Iron Cell Death Pathways Offer a New Two-Front Attack on Liver Cancer
A new review in Medical Oncology argues that simultaneously targeting copper-triggered cuproptosis and iron-dependent ferroptosis could open a powerful two-front ...
Cellular Acyl-CoA Profiling Uncovers Mitochondrial CoA Transporters
In a groundbreaking study poised to reshape our understanding of mitochondrial metabolism, researchers have unveiled the crucial roles of two ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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