Mitochondrial Protein Miro1 Emerges as a Driver of Muscle Insulin Resistance in Type 2 Diabetes
Researchers report that the mitochondrial protein Miro1 accumulates in the skeletal muscle of patients with type 2 diabetes, driven by ...
Tag: mitochondrial fission
Astrocyte Gene ATP13A2 Revealed as a Hidden Brake on Brain Inflammation in Parkinson’s Disease
New research shows that the Parkinson's-linked gene ATP13A2 keeps astrocytic mitochondria in balance, and that its loss triggers excessive mitochondrial ...
Blocking a Mitochondrial Fission Protein Could Strip Head and Neck Cancers of Radiation Resistance
New research shows that blocking the mitochondrial fission protein DRP1 collapses antioxidant defenses in head and neck squamous cell carcinoma, ...
Plant Compounds Emerge as Potential Dual Blockers of Brain-Damaging Enzymes
A computational study identifies plant-derived compounds, notably coumarin, as promising dual inhibitors of the ROCK1 and ROCK2 enzymes that regulate ...
Old Antipsychotic Meets Mitochondrial Blocker in Two-Drug Strike on Cancer Cells
New research shows that pairing the decades-old antipsychotic chlorpromazine with the mitochondrial fission inhibitor mdivi-1 sharply boosts cancer cell death ...
DRP1 Inhibitor DRP1i2 Protects Hearts from Doxorubicin-Induced Damage
Doxorubicin has helped transform the treatment of many cancers, but the drug carries a dangerous biological trade-off: it can damage ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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