Neuronal Drp1 Loss Promotes Hippocampal Neurodegeneration and Synaptic Loss in Aging Mice
A study in middle-aged mice demonstrates that neuronal Drp1 deficiency accelerates hippocampal neurodegeneration, synaptic loss, and memory impairment.
Tag: mitochondria
Mitochondrial Dysfunction Linked to Blood-Brain Barrier Failure
A review in Fluids and Barriers of the CNS links mitochondrial dysfunction to blood-brain barrier failure and explores therapeutic targets.
Flow Cytometry Tracks Mitophagy Variations in Leukemia Cells
New flow cytometry protocols enable robust measurement of mitophagy rates and mitochondrial mass in leukemia cells, revealing higher clearance in ...
Engineering Extended Storage Strategies for Clinical Mitochondrial Transplantation
A narrative review evaluates engineering strategies, stability limits, and standardized benchmarks required to extend the storage of isolated mitochondria for ...
Review Links Mitochondria-ER Contacts to Neurodegeneration
A review in Cell & Bioscience identifies mitochondria-ER contact sites as potential homeostatic hubs linking metabolic stress and neuroinflammation in ...
Naringenin Restores Liver OPA1 Expression in Heat-Stressed Broiler Chickens
Researchers found that naringenin counteracts heat stress-induced downregulation of hepatic OPA1 while reducing biochemical markers of liver injury and oxidative ...
Review Links AhR Receptor to Mitochondrial Stress
A mini review in Frontiers in Cell Death explores how the aryl hydrocarbon receptor influences mitochondrial function through the AhR–CYP1A1–ROS ...
Mitochondrial Mechanisms Regulate Antitumour Immunity and Reveal Potential Cancer Therapies
A review in Clinical and Experimental Medicine examines how mitochondrial metabolism and signalling govern tumour immune evasion and highlight potential ...
Transplanted Mitochondria Rescue Metabolic Function in MELAS Endothelial Cells In Vitro
An in vitro study demonstrates that transplanted healthy mitochondria integrate into MELAS endothelial cells, improving cellular energetics and reducing mutant ...
AI Predicts Thousands of Mitochondrial Protein Interactions Linked to Human Diseases
Texas A&M AgriLife Research scientists used the AI tool AlphaFold-Multimer to identify nearly 2,900 likely mitochondrial protein interactions, revealing potential ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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