Simulating the Microcirculation: How Models Reveal Hidden Blood Vessel Networks
A new review describes theoretical simulation methods for studying blood flow, oxygen exchange, flow regulation and structural remodeling in microvascular ...
Tag: microcirculation
Fluids Can Rescue the Microcirculation in Shock, but No Solution Wins Yet
A new review finds that fluid resuscitation can improve sublingual microcirculation in critically ill patients, but the superiority of any ...
Blood Pressure Targets Alone Fail Patients: Why Surgeons Must Watch Perfusion, Not Just Numbers
A new Perspective argues that fixed mean arterial pressure thresholds of 60–65 mmHg are safety floors, not guarantees of organ ...
PET Scans Guide Computer-Generated Coronary Networks for Heart Blood Flow Simulation
A new adaptive constrained constructive optimization algorithm builds patient-specific coronary arterial networks from PET myocardial perfusion data, enabling pulsatile hemodynamic ...
Sepsis therapies aim to protect the endothelial glycocalyx, review finds
A systematic review of 21 studies, mostly in animals, identifies ascorbic acid, sulodexide, heparin-based therapies and other interventions that may ...
Vasopressor Test Reveals Uneven Capillary Refill Responses in Septic Shock
A pilot study of 32 septic shock patients found that only about one-third improved capillary refill time when mean arterial ...
Thermal Camera Tracks Real-Time Foot Microcirculation During Leg Revascularisation
A deep learning-assisted thermal imaging system tracked real-time microcirculatory changes in the plantar foot during endovascular revascularisation in 21 patients ...
Pneumonia may lead to sepsis through a failing immune boundary, researchers argue
A perspective in Critical Care argues that pneumonia-associated sepsis should be understood as a multidimensional syndrome driven by loss of ...
Why Capillary Refill Time Slows in Sepsis: Six Mechanisms Mapped
A narrative review proposes six mechanisms, ordered by strength of evidence, that may prolong capillary refill time in sepsis and ...
MIF Inhibitor ISO-1 Cuts Liver Reperfusion Injury in Rat Transplant Model
A small-molecule inhibitor of macrophage migration inhibitory factor reduced early liver injury and improved graft microcirculation in a rat model ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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