ADAM17 Enzyme Drives Migration in Canine Mammary Tumor Cells, Study Finds
A new study in BMC Cancer shows that the protease ADAM17 is upregulated in aggressive canine mammary carcinomas and promotes ...
Tag: metastasis
Scientists Uncover a 45-Gene Signature That Predicts Prostate Cancer Spread
Researchers have developed and validated a 45-gene transcriptomic signature, Met-Score, that quantifies metastatic competence in primary prostate tumors and predicts ...
Rare Giant Lung Tumour With Suspected Liver Spread Challenges Diagnosis and Treatment
A case report describes a 57-year-old woman with a giant intrapulmonary solitary fibrous tumour exceeding 16 centimetres, complicated by suspected ...
Misplaced Gap Junction Protein Drives Colorectal Cancer Spread—and Reveals a Drug Weakness
Researchers found that the gap junction protein Cx26 relocates to mitochondria in metastatic colorectal cancer, driving EMT and calcium signaling, ...
Atypical B Cells Emerge as Key Players in Gastric Cancer Spread, Study Finds
A large computational study links TTN/TP53 co-mutations in gastric cancer to a prognostically favorable population of tumor-associated atypical B cells ...
MRI Scans Reveal Hidden Cell Neighborhoods That May Signal Breast Cancer Spread
Researchers at Fudan University Shanghai Cancer Center have linked MRI-visible features such as background parenchymal enhancement and peritumoral edema to ...
Lung Nodules in Breast Cancer Patients Are Often Not Metastases, Major Analysis Finds
A new meta-analysis of 27 studies finds that lung nodules in breast cancer patients are most often primary lung cancer ...
CD39 Emerges as a Deadly Biomarker and Drug Target in Bile Duct Cancer
New research shows that the immune enzyme CD39 is overexpressed in cholangiocarcinoma, drives tumor growth and metastasis through the ANXA2 ...
Dogs’ Insulin-Secreting Tumors Reveal Two Hidden Cancer Cell Types in First-of-Its-Kind Study
The first single-cell RNA sequencing study of naturally occurring insulinoma in any species reveals two distinct insulin-expressing cancer cell populations, ...
Metabolic Shape-Shifters: How Breast Cancer Stem Cells Rewire Their Fuel to Survive and Spread
A new review in Cellular and Molecular Life Sciences details how breast cancer stem cells use flexible metabolic programs and ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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