HSP90 Chaperone Isoforms Emerge as Precision Targets in Lung Cancer
A new review maps how the four HSP90 chaperone isoforms play distinct roles in lung cancer progression and drug resistance, ...
Tag: metabolic reprogramming in cancer
CRISPR Screen Reveals How Ovarian Cancer Cells Resist Niraparib
A genome-wide CRISPR screen identifies UGCG-driven sphingolipid metabolism and protective autophagy as drivers of Niraparib resistance in ovarian cancer.
Computational Study Links Metabolic Enzyme NNMT to a Triple Shield That Lets Cancer Cell Clusters Survive in the Bloodstream
A new computational framework links the metabolic enzyme NNMT to coordinated platelet, neutrophil, and immune exhaustion programs in circulating tumor ...
Rewiring the Tumor Engine: How Metabolism Could Become Cancer’s Next Weak Spot
New research highlights microRNAs, mitochondrial ribosomal proteins and lactate signaling as promising targets against cancer's metabolic reprogramming.
Precision Nutrition: Tailoring Diet to Cancer Treatment Could Redefine Precision Medicine
A new narrative review argues that individualized dietary interventions, grounded in tumor metabolism and the gut microbiome, should be integrated ...
Lactate Tag on Histones Fuels Drug Resistance in Head and Neck Cancer
New research shows that CBP-driven histone H3K18 lactylation activates GLI2 transcription, promoting head and neck squamous cell carcinoma progression and ...
c-MET Signaling Reshapes the Lung Cancer Immune Landscape in Space and Metabolism
A new review in the Journal of Translational Medicine argues that c-MET signaling shapes spatially confined, metabolically driven immunosuppressive niches ...
Metabolic Shape-Shifters: How Breast Cancer Stem Cells Rewire Their Fuel to Survive and Spread
A new review in Cellular and Molecular Life Sciences details how breast cancer stem cells use flexible metabolic programs and ...
Ketogenic Diet May Prime the Body to Fight Cancer by Rewiring Metabolism and Immunity
A new review argues that the ketogenic diet may act as a systems-level sensitization platform in cancer therapy by simultaneously ...
RNA Tagging Enzyme METTL16 Fuels Colorectal Cancer by Hijacking Amino Acid Metabolism and Silencing Immune Cells
New research shows that the RNA methyltransferase METTL16 drives colorectal cancer growth and immune evasion by stabilizing BCAT1 mRNA and ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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