Scientists Engineer Delivery Systems to Turn Mitochondria Into Precise Therapies
A new Perspective in Science Bulletin outlines engineered delivery systems, including surface coatings, cell carriers, protective vesicles, and targeting platforms, ...
Tag: mesenchymal stem cells
Beyond cell transplants: The next frontier in mesenchymal stem/stromal cell therapy and regenerative medicine
The reframing of mesenchymal stem and stromal cells as regulatory hubs rather than building blocks represents more than a semantic ...
Bacterial Peptide-Primed Stem Cell Vesicles Push Colon Cancer Cells Toward Suicide
Researchers preconditioned mesenchymal stem cells with the bacterial peptide plantaricin, producing smaller, protein-rich microvesicles that selectively triggered apoptosis in colon ...
MSC-Derived Extracellular Vesicles May Reprogram the Inflamed Spinal Cord After Injury — But the Road to the Clinic Is Steep
A comprehensive review maps how MSC-derived extracellular vesicles modulate the inflammatory microenvironment after spinal cord injury across acute, subacute, and ...
IL-18 Cytokine Drives Inflammatory Senescence and Blocks Skeletal Regeneration
Macrophage-derived IL-18 triggers inflammatory senescence and feed-forward inflammation that suppresses mesenchymal stem cell osteogenesis, impairing skeletal regeneration in mice and ...
Landmark Study Linking a MicroRNA to Stem Cell Survival in Alzheimer’s Models Is Rettracted Over Image Integrity Concerns
Frontiers in Neuroscience has retracted a 2018 study on microRNA Let-7f-5p and stem cell survival in Alzheimer's disease models after ...
Molecular brake discovery points to stronger ultrasound-driven bone healing
Researchers at Capital Medical University have identified Id3 as a molecular brake that limits ultrasound-induced bone formation and shown that ...
Enzyme That Softens Tissue Barriers Could Open the Nose-to-Brain Route for Gene Therapy
A new narrative review outlines how hyaluronidase can transiently open the hyaluronic acid-rich extracellular matrix to enhance nose-to-brain delivery of ...
Cancer Protein LGALS3BP Reshapes the Cargo of Neuroblastoma Extracellular Vesicles
New research links the secreted glycoprotein LGALS3BP to selective enrichment of microRNAs and the RNA-binding protein SRSF1 in neuroblastoma extracellular ...
Stem Cell Platform Predicts Chemotherapy Damage to Healthy Tissue Better Than Animal Tests
Hungarian researchers have built a human induced pluripotent stem cell platform that reproduces the sensitivity of healthy dividing tissues to ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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