Tag: medicinal chemistry

A new computational Perspective argues that flavonoids, exemplified by the soy isoflavone daidzein, are a largely untapped and rationally designable ...

Chemists have fused pyrimidine and 1,3,4-oxadiazole rings into a new family of hybrid molecules, and the best member kills breast, ...

Researchers used QSAR modelling and molecular docking to identify pyridine-based oxazolidinone derivatives that bind the bacterial ribosome more tightly than ...

A sweeping review of 2020-2025 literature shows that Mannich-type multicomponent reactions have become the fastest, greenest route to piperazine-based molecules ...

Egyptian researchers used lanthanum hydroxide nanorods to synthesize a triazolopyrimidine compound that kills Trichinella spiralis larvae and adult worms at ...

A new disubstituted thymoquinone derivative designated TQ13 inhibited TLR2 and TLR4 signaling and protected kidney function in diabetic rats, offering ...

Scientists at Caltech and the University of Pittsburgh have engineered haemproteins to convert simple unactivated alkenes directly into chiral oxazolidinone ...

A 58-article special issue of Molecular Diversity shows how synthetic chemistry, protein degraders, natural products, and AI-driven screening are converging ...

Researchers have identified a morpholine-substituted chalcone, TC12, that inhibits monoamine oxidase B at 11 nanomolar with over 3,600-fold selectivity and ...

Yale chemists have developed a two-step electrosynthesis that converts carbon dioxide, nitrite and aromatic aldehydes into valuable arylglycine amino acids ...