Designer Molecules That Outperform Vitamin C Could Keep Fresh Beef Red for Longer
Chemists synthesized ten indole-thiosemicarbazide hybrids, with one compound outperforming vitamin C in radical-scavenging assays and preserving the red color of ...
Tag: medicinal chemistry
Benzothiazole Emerges as a Promising Weapon Against Drug-Resistant Malaria
A new review argues that benzothiazole derivatives, acting through DHFR inhibition and heme detoxification, could yield next-generation antimalarials effective against ...
Quinone-Based Metal Complexes Show Promise as Antibiotics and Rust Fighters
Chemists have synthesized six divalent metal complexes of a naphthoquinone-based Schiff base ligand that show strong antimicrobial activity against Staphylococcus ...
Arthritis Drug Turned Molecular Weapon Strikes a Rare Lung Pathogen
Chemists have converted the anti-inflammatory drug diflunisal into fluorinated biphenyl ureas that kill Mycobacterium kansasii at nanomolar-scale concentrations while leaving ...
Chemists Swap Oxygen for Sulfur in Four-Membered Rings in a Single Step
Researchers report a one-step skeletal editing reaction that converts readily available oxetanes into thietanes using thiourea, enabling direct oxygen-to-sulfur atom ...
Star Chemist John Bower Takes Up Multimillion-Pound Chair at Bath to Boost Drug Discovery
The University of Bath has appointed Professor John Bower, formerly Regius Professor of Chemistry at Liverpool, as the new Raymond ...
Purine Scaffold Powers a New Generation of Drug Candidates Across Cancer and Infectious Disease
A comprehensive review maps how strategic chemical modifications to the purine scaffold yield potent drug candidates against cancer, malaria, drug-resistant ...
AI Chemists Learn Where to Break Molecules: Active Learning Steers Drug Discovery Reactions
Researchers at ETH Zurich and Roche have combined active learning with geometric and self-supervised deep learning to predict C–H borylation ...
Nitrofuran-Tweaked Ciprofloxacin Analogues Show Potent Activity Against Resistant Staphylococcus aureus
Chemists have fused nitrofuran groups onto ciprofloxacin to create hybrid antibiotics up to sixteen times more potent than the original ...
Ohio State Chemist David Nagib Wins 2026 Blavatnik National Award for Radical Drug Discovery
Ohio State chemist David Nagib has been named a 2026 Blavatnik National Awards laureate for pioneering radical and carbene chemistry ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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