How Tumor Stiffness May Rewire RNA Chemistry to Help Cancers Evade Immunity
A new review in Molecular Cancer proposes that mechanical forces within tumors can reprogram RNA modifications, offering a fresh framework ...
Tag: mechanotransduction
Blood Vessel Protein Epac1 Found to Fuel Melanoma Growth Through YAP/TAZ Signalling
New research shows that the endothelial protein Epac1 drives melanoma growth and angiogenesis by coordinating VEGFR2 signalling, RhoA-dependent cytoskeletal dynamics, ...
Tumour Matrisome Emerges as a Rich Source of Cancer Biomarkers and Drug Targets
A new review in Nature Reviews Clinical Oncology details how the tumour extracellular matrix, or matrisome, drives cancer progression and ...
Calcium Channel TRPV4 Emerges as a Key Player in Marfan Syndrome Aortic Disease
A new study identifies the mechanosensitive calcium channel TRPV4 as a top candidate driving the inflammatory and remodeling behavior of ...
How the Bladder Senses Force: Biomechanics of Injury and Repair
A sweeping new review in Nature Reviews Urology reveals how mechanical forces such as stretch, pressure and shear stress actively ...
Tissue Flow Acts as a Guidance Cue for Immune Cell Polarization and Migration
New research in Xenopus embryos shows that flowing ectodermal tissue physically guides the polarization and directional migration of embryonic immune ...
How Microbial Adhesion Switches On Piezo1 to Launch Innate Immunity
A new Nature Immunology study shows that microbial adhesion to myeloid cells activates the mechanosensitive ion channel Piezo1, triggering a ...
Fibroblasts With a Stem Cell Marker Help Skin Adapt to Mechanical Stress
A new Nature Communications study shows that LGR5-positive fibroblasts coordinate how skin adapts to mechanical stress through JAK1-dependent signaling pathways.
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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