LCN2 loss reduces invasion and alters stress pathways in TNBC cells
A CRISPR knockout study in MDA-MB-231 triple-negative breast cancer cells links LCN2 loss to reduced migration, invasion and substrate-dependent adhesion, ...
Tag: MDA-MB-231
Old Antipsychotic Meets Mitochondrial Blocker in Two-Drug Strike on Cancer Cells
New research shows that pairing the decades-old antipsychotic chlorpromazine with the mitochondrial fission inhibitor mdivi-1 sharply boosts cancer cell death ...
Lifeguard Protein Rewires Stress Genes in Triple-Negative Breast Cancer Cells
Silencing the anti-apoptotic protein Lifeguard in triple-negative breast cancer cells alters intracellular calcium levels and reshapes the expression of endoplasmic ...
Coated Ferrite Nanoparticles Show Potent, Dose-Dependent Killing of Breast Cancer Cells
A team of researchers has synthesized polyacrylic acid-coated cobalt, nickel, and zinc ferrite nanocomposites and demonstrated dose-dependent cytotoxicity against MCF-7 ...
Copper Supercharges Beta-Carboline Metal Complexes Against Aggressive Breast Cancer
New nickel and copper metallocarboxylate complexes of a tryptophan-derived beta-carboline alkaloid bind DNA in the minor groove and show dramatic, ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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