Plant Flavonoids Emerge as Multi-Target Weapon Against Drug-Resistant Tuberculosis
A new review maps how plant-derived flavonoids attack tuberculosis through multiple molecular mechanisms while outlining the structural features and delivery ...
Tag: MAPK signaling
Silencing PD-L1 Reveals a Hidden Phosphatase Axis That May Drive Gastric Cancer Survival
New research shows that silencing the PD-L1 gene in gastric cancer cells reshapes the expression of MAPK-regulating DUSP phosphatases, revealing ...
How a Common Grain Toxin Hijacks Cells—and How Probiotics Fight Back
A new review maps how the mycotoxin deoxynivalenol hijacks ribosomal and cellular signaling networks to drive intestinal, immune, neurological and ...
Tight Junction Protein Revealed as Hidden Brake on Kidney Cancer Growth
Researchers report that the tumor-suppressive protein TJP2 stabilizes TIMM21, which boosts SPRY4 and dampens ERK1/2 signaling to restrain clear cell ...
How a Single Gene Loss Helps Melanoma Outsmart Targeted Drugs
An integrative multi-omics study reveals how loss of the chromatin factor ARID1A rewires receptor and kinase signaling in melanoma, driving ...
Seaweed, Microbes and Humic Acids Rewire Plant Chemistry to Boost Medicinal Alkaloids
A new review explains how biostimulants such as seaweed extracts, humic substances, and beneficial microbes act as signaling agents that ...
How Lung Cancers Shed Their Identity to Outsmart KRAS Drugs
A new mouse study shows that lung adenocarcinomas can evade KRAS inhibitors by reprogramming their cellular identity through transcription factors ...
Methylmercury Rewires Brain Cell Genes at Doses That Leave Cells Alive
A new transcriptomic study reveals that non-lethal methylmercury exposure disrupts gene expression, microRNA regulation, and ion transport in rat neuronal ...
Fungal Allies Decoded: How Trichoderma Rewires Melon Roots to Defeat Fusarium Wilt
A new transcriptomic study reveals how Trichoderma asperellum and T. gamsii reprogram melon root defense genes and suppress Fusarium pathogen ...
Master Switch in Apple Rot Fungus Links Nitrogen Metabolism to Virulence
Scientists show that the GATA transcription factor BdAreA controls nitrogen use, stress tolerance, and disease-causing power in the apple ring ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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