A Missing Lipid Tag on PDZK1 Emerges as a Hidden Cause of Sluggish Sperm
Researchers found that defective palmitoylation of the protein PDZK1 at cysteine 10, mediated by ZDHHC5, disrupts epididymosome-mediated cholesterol transport and ...
Tag: male infertility
Liver Drug Shows Promise for Restoring Sperm Quality in Metabolic Syndrome
A new mouse study shows that the FXR agonist obeticholic acid improves sperm progressive motility in high-fat diet-induced metabolic syndrome ...
Scientists Discover a Molecular Switch That Drains Sperm of Their Swimming Power at High Altitude
New research identifies the free fatty acid receptor FFAR4 as a key mediator of high-altitude hypoxia-induced sperm motility loss, showing ...
Gut Microbes to the Rescue: Probiotics Shield Kidneys and Sperm From E. coli Damage in Rats
A new rat study shows that a three-strain Lactobacillus probiotic and its cell-free postbiotic significantly reduce kidney and testicular damage, ...
Kisspeptin-10 Shows Promise Against Obesity-Driven Testicular Damage in Rat Study
A new rat study shows the puberty-regulating hormone Kisspeptin-10 reduces testicular oxidative stress, improves sperm quality, and boosts mitophagy-related proteins ...
Metabolite Fingerprint in Seminal Plasma Could Explain Hidden Male Infertility
A systematic review of twenty metabolomic studies has identified consistently deregulated metabolites in the seminal plasma of infertile men, pointing ...
Recycling Machinery in Sertoli Cells Proves Essential for Male Fertility
A Sertoli cell-specific Beclin1 knockout study in mice reveals that autophagy in these nurse cells underpins the blood-testis barrier and ...
Tiny RNA Fragment in Sperm Tracks Severity of Varicocele-Linked Infertility
Researchers report the first evidence that sperm tRNA-derived fragments are altered in varicocele, with tRF-36 significantly downregulated in the most ...
Sphingolipid Metabolism Emerges as a Hidden Driver of Male Infertility
New research links disrupted sphingolipid metabolism to sperm production failure in non-obstructive azoospermia, combining human bioinformatics with a busulfan mouse ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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