Brain Scans Reveal How Mood Disorder Symptoms Map onto Cortical Structure
A large structural MRI study finds that data-driven symptom phenotypes spanning depression and bipolar disorder map onto distinct, modality-specific patterns ...
Tag: major depressive disorder
Stress Silences an RNA-Binding Protein in the Hippocampus, Revealing a New Antidepressant Pathway
A new mouse study shows that the RNA-binding protein TIA1 in ventral hippocampal CA1 excitatory neurons protects against depressive-like behaviors ...
Brain Receptor Pair Reveals Why Some Antidepressants Work Faster Than Others
A new mouse study shows that a complex between the sigma-1 receptor and the serotonin 1A receptor disinhibits a key ...
Experimental Kv7 Channel Opener Azetukalner Fails Brain Imaging Endpoint but Shows Hints of Benefit in Depression
A phase II randomized controlled trial found that the Kv7 channel opener azetukalner did not significantly alter reward-related brain activity ...
Blood Protein Could Predict Which Depressed Teens Respond to Brain Stimulation
A randomized trial in adolescents with depression found that baseline suPAR levels predicted response to rTMS while early changes in ...
High-Dose LSD Boosts Working Memory Brain Signals in Depression Trial
A randomized trial found that high-dose LSD treatment significantly increased working memory-related brain activity in patients with major depressive disorder, ...
AI Tracks Broken Reference Chains in Speech to Map How Meaning Unravels in Schizophrenia and Depression
A new study shows that an automatic coreference resolution model performs worse on the speech of people with schizophrenia and ...
Blood Clues to Teen Suicidal Thoughts Diverge Sharply Between Boys and Girls
A study of 319 adolescents with major depressive disorder finds that suicidal ideation is linked to distinct blood-based immune and ...
Brain Wiring Reveals Opposite Signatures in Bipolar Depression and Major Depression
A multimodal neuroimaging study finds that bipolar depression and major depressive disorder show opposite patterns of static brain network connectivity, ...
Ketamine-Derived Nasal Spray Drug Shows Promise Against Loss of Pleasure in Depressed Teens
A randomized controlled trial in China found that adjunctive esketamine infusions significantly improved anhedonia, depressive symptoms, and suicidal symptoms in ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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