Tag: macrophages

Rapamycin treatment reprogrammed the aging immune system in atherosclerotic mice, reducing plaque macrophages and neutrophils, expanding regulatory T cells, and ...

Researchers have replaced the toxic components of a macrophage-directed immunotherapy for Ewing sarcoma with cyclophosphamide and the erythrocyte-sparing antibody lemzoparlimab, ...

New research shows that alpha-synuclein, best known for its role in Parkinson's disease, enters macrophages through the protein FLOT1, blocks ...

A combined single-cell and genetic analysis identifies the stress-response gene HSPA1B as a cell-type-specific molecular bridge between COPD and atherosclerosis.

New research shows that African swine fever virus extensively reorganizes host chromatin architecture and RNA polymerase II activity within hours ...

A multi-omics study finds that LDL cholesterol metabolism reshapes macrophages and tumor cells in head and neck squamous cell carcinoma, ...

A first-of-its-kind multi-omics study shows that dogs and humans share key genetic drivers and conserved tumor microenvironment features in hepatocellular ...

A new study shows that the two pyranocoumarins decursin and decursinol angelate reproduce the major anti-inflammatory and antioxidant effects of ...

Scientists engineered hypoxia-preconditioned macrophage vesicles that display apoptotic eat-me signals and, when delivered in a GelMA hydrogel, reprogram inflammation and ...

An experimental oral FGFR1 agonist called SUN11602 reduced inflammation, preserved nerve architecture and enhanced Schwann cell activity in the first ...