Zinc Nanovaccine Retrains Immune Cells to Attack Lung Cancer
A mannose-decorated zinc metal-organic framework nanovaccine delivering the tumor antigen CLDN6 reprograms immunosuppressive macrophages in lung tumors into antigen-presenting cells ...
Tag: macrophage reprogramming
Staphylococcal Protein Reprograms Liver Tumor Macrophages to Boost Immunotherapy
A bacterial protein called LukS-PV reprograms immunosuppressive macrophages in liver cancer by targeting the human C5aR1 receptor, restoring CD8-positive T-cell ...
Biomimetic MoSe2 Nanozymes Boost Implant Soft Tissue Healing on Two Fronts
Scientists have built a macrophage-membrane-coated MoSe2 nanozyme that simultaneously targets S. aureus and rescues oxidative-stressed immune cells, markedly improving peri-implant ...
DNMT1-Targeted Macrophages Deliver Drug-Loaded Nanoparticles to Reduce Heart Transplant Fibrosis
Heart transplantation can replace a failing organ, but the procedure does not end the biological struggle. Even when a graft ...
Engineered macrophages reprogram tumor microenvironments, boosting antitumor immunity with IL-10–TLR9 switches
Cancer immunotherapy has transformed treatment for some patients, yet many solid tumors remain protected by a hostile biological environment that ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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