Citrus-Derived Flavonoid Didymin Shows Promise for Healing Tendon-Bone Injuries
A new mouse study shows the natural flavonoid didymin promotes tendon-bone healing by reprogramming macrophage metabolism through PPAR-mediated fatty acid ...
Tag: M2 macrophages
Sphingosine Rheostat Reemerges as an Immune Suppression Switch in Metastatic Colorectal Cancer
A large multi-omics study repositions the classic sphingosine-1-phosphate/ceramide rheostat from tumor cells to the stromal-immune compartment, linking the lipid imbalance ...
Ancient Chinese Herbal Formula Shows Promise Against Disc Degeneration
A classical Chinese herbal formula, Juanbi Tang, attenuates intervertebral disc degeneration in rats by suppressing p38MAPK/NF-κB signaling, activating Atg5-dependent autophagy, ...
OLR1 Emerges as Key Driver of Gastric Cancer Growth and Immune Evasion
A new study shows that the lipid receptor OLR1 drives gastric cancer progression by activating NF-κB signaling and polarizing macrophages ...
Newly Discovered Trypsinogen Variants Drive Immune Responses in IgG4-Related Disease
Researchers identified novel PRSS1 trypsinogen variants in IgG4-related disease tissue and linked them to M2 macrophage-driven type 2 immune responses.
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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